منابع مشابه
Adiponectin and vulnerable atherosclerotic plaques.
High-risk plaques that are vulnerable to rupture demonstrate distinct morphological characteristics. They are differentiated from the lesions responsible for stable coronary artery disease by their large necrotic cores, thin-inflamed fibrous caps, and positive remodeling. Adiponectin is an adipocytokine that is reduced in obesity and type 2 diabetes. Hypoadiponectinemia has been associated with...
متن کاملDetection and treatment of vulnerable plaques and vulnerable patients: novel approaches to prevention of coronary events.
There is growing interest in the possibility that identification and treatment of vulnerable plaques and vulnerable patients can enhance the progress made against coronary artery disease. Innovations in medical therapy—statins and other agents—and novel interventional cardiology techniques— eg, drug-eluting stents— have significantly decreased the morbidity and mortality caused by coronary athe...
متن کاملVulnerable plaques, inflammation and newer imaging modalities.
Currently, inflammation is considered to be the central player in the pathogenesis of atherosclerosis. It leads to the formation of multiple plaques in the arterial beds including coronary vasculature. Recent studies using the latest imaging techniques have shown that in patients with acute coronary syndromes (ACS) multiple plaques are ruptured and have thrombus formation on them. Various facto...
متن کاملVulnerable plaques: from PROSPECT to prospects….
c a c k p n p n c T s t W d o s a f l f odern cardiology can definitely pride itself for developing techniques designed to restore blood flow in coronary arteries with tight lesions that ause myocardial ischemia or in the aftermath of n acute myocardial infarction (MI). However, espite the advances in diagnosis and intervenion, a substantial number of patients continue to uffer acute adverse ev...
متن کاملMathematical models for vulnerable plaques: MPI
A plaque is an accumulation and swelling in the artery walls and typically consists of cells, cell debris, lipids, calcium deposits and fibrous connective tissue. A person is likely to have many plaques inside his/her body even if they are healthy. However plaques may become “vulnerable”, “high-risk” or “thrombosis-prone” if the person engages in a high-fat diet and does not exercise regularly....
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2018
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2018.06.079